Article
Maternal-fetal DNA admixture is associated with intrapartum mother-to-child transmission of HIV-1 in Blantyre, Malawi.
The Journal of infectious diseases - 15 May 2008
Kwiek Jesse J, Arney Leslie A, Harawa Visopo, Pedersen Bonnie, Mwapasa Victor, Rogerson Stephen J, Meshnick Steven R
Abstract excerpt
BACKGROUND: The mechanism of mother-to-child transmission (MTCT) of HIV-1 is not well described. METHODS: Of 328 HIV-infected mother-infant pairs, we identified 91 that had discordant angiotensin I-converting enzyme and glutathione S-transferase M1 alleles. Maternal alleles in cord blood were quantified with real-time polymerase chain reaction, as indicators of microtransfusions. RESULTS: HIV-1 infected infants...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
