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Different Regions of HIV-1 Subtype C<i>env</i>Are Associated with Placental Localization and<i>In Utero</i>Mother-to-Child Transmission

5 May 2011

Abstract excerpt

HIV infections are initiated by a limited number of variants that diverge into a diverse quasispecies swarm. During in utero mother-to-child transmission (IU MTCT), transmitted viral variants must pass through multiple unique environments, and our previously published data suggest a nonstochastic model of transmission. As an alternative to a stochastic model of viral transmission, we hypothesize that viral...

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PMID: 21543508
DOI: 10.1128/jvi.01955-10

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