Genetic variations of GAK in two Chinese Parkinson's disease populations: a case-control study.

doi:10.1371/journal.pone.0067506

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Article

Genetic variations of GAK in two Chinese Parkinson's disease populations: a case-control study.

PloS one - 1 Jan 2013

Tseng Wei-En Johnny, Chen Chiung-Mei, Chen Yi-Chun, Yi Zhao, Tan Eng-King, Wu Yih-Ru

Abstract excerpt

Cyclin G-associated kinase (GAK) modifies α-synuclein expression levels and affects the susceptibility of Parkinson's disease (PD). The single-nucleotide polymorphism (SNP) rs1564282 of GAK gene has a significant association to the risk of PD among Caucasian populations. To date there is only one data with regards to ethnic Chinese from Mainland China. Here, we conducted a case-control study in two independent...

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PMID: 23826309
DOI: 10.1371/journal.pone.0067506
PMCID: PMC3691170

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