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Article

Screening and Improving the Recombinant Nitrilases and Application in Biotransformation of Iminodiacetonitrile to Iminodiacetic Acid.

PloS one - 1 Jan 2013

Liu Zhi-Qiang, Baker Peter James, Cheng Feng, Xue Ya-Ping, Zheng Yu-Guo, Shen Yin-Chu

Abstract excerpt

In this study, several nitrilase genes from phylogenetically distinct organisms were expressed and purified in E. coli in order to study their ability to mediate the biotransformation of nitriles. We identified three nitrilases: Acidovorax facilis nitrilase (AcN); Alcaligenes fecalis nitrilase (AkN); and Rhodococcus rhodochrous nitrilase (RkN), which catalyzed iminodiacetonitrile (IDAN) to iminodiacetic acid...

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Identifiers

PMID: 23826231
DOI: 10.1371/journal.pone.0067197
PMCID: PMC3695085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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