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Development of efficient nitrilase biocatalysts through growth selection for acetonitrile wastewater detoxification.

Bioresource technology - 1 Oct 2026

Wang Hua, Wang Chen, Kuang Peiming, Chen Qiwei, Sun Hongxu, Sun Haichuan, Miao Jincheng, Chang Yanhong, Luo Hui

Abstract excerpt

Acetonitrile wastewater poses serious threat to both the ecological environment and human health. Conventional chemical hydrolysis of acetonitrile typically requires harsh conditions-elevated temperatures and strong acids or bases - leading to the generation of substantial undesirable by-products and inorganic waste. In contrast, nitrilase can directly hydrolyze nitriles groups into carboxylic acids in a single...

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PMID: 42219119
DOI: 10.1016/j.biortech.2026.135033

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