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Article

SERPINA2 is a novel gene with a divergent function from SERPINA1.

PloS one - 1 Jan 2013

Marques Patrícia Isabel, Ferreira Zélia, Martins Manuella, Figueiredo Joana, Silva Diana Isabel, Castro Patrícia, Morales-Hojas Ramiro, Simões-Correia Joana, Seixas Susana

Abstract excerpt

Serine protease inhibitors (SERPINs) are a superfamily of highly conserved proteins that play a key role in controlling the activity of proteases in diverse biological processes. The SERPIN cluster located at the 14q32.1 region includes the gene coding for SERPINA1, and a highly homologous sequence, SERPINA2, which was originally thought to be a pseudogene. We have previously shown that SERPINA2 is expressed in...

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Share to alpha 1-Antitrypsin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23826168
DOI: 10.1371/journal.pone.0066889
PMCID: PMC3691238

Genes

SERPINA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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