SerpinB3: A Multifaceted Player in Health and Disease – Review and Future Perspectives

Abstract excerpt

SerpinB3, a member of the serine-protease inhibitor family, has emerged as a crucial player in various physiological and pathological processes. Initially identified as an oncogenic factor in squamous cell carcinomas, SerpinB3's intricate involvement extends from fibrosis progression and cancer to cell protection in acute oxidative stress conditions. This review explores the multi-faceted roles of SerpinB3, f...

Topics

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• Antioxidant Activity and Oxidative Stress
• Blood Coagulation and Thrombosis Mechanisms
• Cell death mechanisms and regulation
• Disease Models, Animal
• Evolution, Molecular
• Genetic Variation
• Mice
• Protease and Inhibitor Mechanisms

Identifiers and source

Literature Corpus work

e2025f9f-f917-538a-b30f-ea7bd5356a72

DOI

10.20944/preprints202406.0851.v1