Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enriched environment-induced maternal weight loss reprograms metabolic gene expression in mouse offspring.

The Journal of biological chemistry - 20 Feb 2015

Wei Yanchang, Yang Cai-Rong, Wei Yan-Ping, Ge Zhao-Jia, Zhao Zhen-Ao, Zhang Bing, Hou Yi, Schatten Heide, Sun Qing-Yuan

Abstract excerpt

The global prevalence of weight loss is increasing, especially in young women. However, the extent and mechanisms by which maternal weight loss affects the offspring is still poorly understood. Here, using an enriched environment (EE)-induced weight loss model, we show that maternal weight loss improves general health and reprograms metabolic gene expression in mouse offspring, and the epigenetic alterations can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Lipid Metabolism

Share to Maternal Exposure

Share to Pregnancy

Share to Weight Loss

Source

Open in PubMed Open full text

Identifiers

PMID: 25555918
DOI: 10.1074/jbc.M114.605642
PMCID: PMC4335202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enriched environment-induced maternal weight loss reprograms metabolic gene expression in mouse offspring.PMID 25555918Read ↗

Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice.Semantic proximity Read ↗

Maternal Western-Style High Fat Diet Induces Sex-Specific Physiological and Molecular Changes in Two-Week-Old Mouse OffspringSemantic proximity Read ↗

Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic disordersSemantic proximity Read ↗

Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gainSemantic proximity Read ↗

Epigenetic Changes Associated With Obesity-related Metabolic ComorbiditiesSemantic proximity Read ↗

Childhood obesity from the genes to the epigenome.Semantic proximity Read ↗

Maternal Diets Trigger Sex-Specific Divergent Trajectories of Gene Expression and Epigenetic Systems in Mouse PlacentaSemantic proximity Read ↗

Epigenomics, gestational programming and risk of metabolic syndrome.Semantic proximity Read ↗

Recent developments on the role of epigenetics in obesity and metabolic diseaseSemantic proximity Read ↗

Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific mannerSemantic proximity Read ↗

Assisted reproduction causes placental maldevelopment and dysfunction linked to reduced fetal weight in miceSemantic proximity Read ↗

The Effects of High-Fat Diet Exposure In Utero on the Obesogenic and Diabetogenic Traits Through Epigenetic Changes in Adiponectin and Leptin Gene Expression for Multiple Generations in Female MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.