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Article

DNA hypomethylation of inflammation-associated genes in adipose tissue of female mice after multigenerational high fat diet feeding.

International journal of obesity (2005) - 1 Feb 2014

Ding Y, Li J, Liu S, Zhang L, Xiao H, Li J, Chen H, Petersen R B, Huang K, Zheng L

Abstract excerpt

OBJECTIVE: Maternal obesity significantly increases the susceptibility of offspring to develop obesity and chronic diseases in adulthood. The offspring of obese mothers are shown to prefer high fat diet (HFD) due to their altered neural circuitry, creating a 'feed-forward cycle' across generations. We hypothesized that the 'feed-forward cycle' caused by multigenerational HFD feeding would have exacerbated effects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23736364
DOI: 10.1038/ijo.2013.98

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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