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Article

Epigenetic contribution to obesity.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2020

Ouni Meriem, Schürmann Annette

Abstract excerpt

Obesity is a worldwide epidemic and contributes to global morbidity and mortality mediated via the development of nonalcoholic fatty liver disease (NAFLD), type 2 diabetes (T2D), cardiovascular (CVD) and other diseases. It is a consequence of an elevated caloric intake, a sedentary lifestyle and a genetic as well as an epigenetic predisposition. This review summarizes changes in DNA methylation and microRNAs...

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Identifiers

PMID: 32279091
DOI: 10.1007/s00335-020-09835-3
PMCID: PMC7368865

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