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Characterization of the African Swine Fever Virus Decapping Enzyme during Infection

12 Oct 2017

Abstract excerpt

ABSTRACT African swine fever virus (ASFV) infection is characterized by a progressive decrease in cellular protein synthesis with a concomitant increase in viral protein synthesis, though the mechanism by which the virus achieves this is still unknown. Decrease of cellular mRNA is observed during ASFV infection, suggesting that inhibition of cellular proteins is due to an active mRNA degradation process. ASFV...

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PMID: 29021398
DOI: 10.1128/jvi.00990-17

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