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Article

Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel.

Proceedings of the National Academy of Sciences of the United States of America - 16 Jul 2013

Du Yuzhe, Nomura Yoshiko, Satar Gul, Hu Zhaonong, Nauen Ralf, He Sheng Yang, Zhorov Boris S, Dong Ke

Abstract excerpt

Pyrethroid insecticides are widely used as one of the most effective control measures in the global fight against agricultural arthropod pests and mosquito-borne diseases, including malaria and dengue. They exert toxic effects by altering the function of voltage-gated sodium channels, which are essential for proper electrical signaling in the nervous system. A major threat to the sustained use of pyrethroids for...

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Identifiers

PMID: 23821746
DOI: 10.1073/pnas.1305118110
PMCID: PMC3718148

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel.PMID 23821746Read ↗

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