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Article

THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge.

European journal of human genetics : EJHG - 1 Mar 2014

Bondar Constanza, Plaza-Izurieta Leticia, Fernandez-Jimenez Nora, Irastorza Iñaki, Withoff Sebo, Wijmenga Cisca, Chirdo Fernando, Bilbao Jose Ramon

Abstract excerpt

Celiac disease (CD) is an immune mediated, polygenic disorder, where HLA-DQ2/DQ8 alleles contribute around 35% to genetic risk, but several other genes are also involved. Genome-wide association studies (GWASs) and the more recent immunochip genotyping projects have fine-mapped 39 regions of genetic susceptibility to the disease, most of which harbor candidate genes that could participate in this disease process....

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Source

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Identifiers

PMID: 23820479
DOI: 10.1038/ejhg.2013.136
PMCID: PMC3925264

Genes

THEMIS
PTPRK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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