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Article

Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.

Arthritis research & therapy - 2 Jun 2013

Lester Susan, Stokes Leanne, Skarratt Kristen K, Gu Ben J, Sivils Kathy L, Lessard Christopher J, Wiley James S, Rischmueller Maureen

Abstract excerpt

INTRODUCTION: The aim of this study was to examine the association between functional polymorphisms in the pro-inflammatory P2X7 receptor and the Ro/La autoantibody response in primary Sjögren's syndrome (pSS). METHODS: Twelve functional P2RX7 polymorphisms were genotyped in 114 pSS patients fulf...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23819992
DOI: 10.1186/ar4248
PMCID: PMC3979150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23819992-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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