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Article

Multiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia.

BMC genomics - 1 Jan 2013

Xie Li, Ng Clara, Ali Thahmina, Valencia Raoul, Ferreira Barbara L, Xue Vincent, Tanweer Maliha, Zhou Dan, Haddad Gabriel G, Bourne Philip E, Xie Lei

Abstract excerpt

BACKGROUND: It is a great challenge of modern biology to determine the functional roles of non-synonymous Single Nucleotide Polymorphisms (nsSNPs) on complex phenotypes. Statistical and machine learning techniques establish correlations between genotype and phenotype, but may fail to infer the bi...

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PMID: 23819581
DOI: 10.1186/1471-2164-14-S3-S9
PMCID: PMC3665574

Genes

EGFR
HDAC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23819581-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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