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Interpretation of complex DNA profiles using empirical models and a method to measure their robustness.

Forensic science international. Genetics - 1 Mar 2008

Gill Peter, Curran James, Neumann Cedric, Kirkham Amanda, Clayton Tim, Whitaker Jonathan, Lambert Jim

Abstract excerpt

A new methodology is presented in order to report complex DNA profiles. We have brought together a number of different theories in order to devise a new protocol to interpret complex cases using likelihood ratios. The calculations are designed to be highly conservative and are widely applicable. We apply a low copy number (LCN) interpretation framework, which includes the probabilities of dropout and...

Topics

Alleles
Computer Simulation
DNA
DNA Fingerprinting
Databases, Factual
Forensic Medicine
Heterozygote
Humans
Likelihood Functions
Microsatellite Repeats
Models, Biological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Statistical

Probability

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Identifiers

PMID: 19083804
DOI: 10.1016/j.fsigen.2007.10.160

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