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Evaluation of low-template DNA profiles using peak heights.

Statistical applications in genetics and molecular biology - 1 Oct 2016

Steele Christopher D, Greenhalgh Matthew, Balding David J

Abstract excerpt

In recent years statistical models for the analysis of complex (low-template and/or mixed) DNA profiles have moved from using only presence/absence information about allelic peaks in an electropherogram, to quantitative use of peak heights. This is challenging because peak heights are very variable and affected by a number of factors. We present a new peak-height model with important novel features, including...

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Identifiers

PMID: 27416618
DOI: 10.1515/sagmb-2016-0038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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