Article
Aberrant DNA methylation of miR-219 promoter in long-term night shiftworkers.
Environmental and molecular mutagenesis - 1 Jul 2013
Shi Fengqin, Chen Xinyi, Fu Alan, Hansen Johnni, Stevens Richard, Tjonneland Anne, Vogel Ulla B, Zheng Tongzhang, Zhu Yong
Abstract excerpt
The idea that shiftwork may be carcinogenic in humans has gained widespread attention since the pioneering work linking shiftwork to breast cancer over two decades ago. However, the biomolecular consequences of long-term shiftwork exposure have not been fully explored. In this study, we performed a genome-wide CpG island methylation assay of microRNA (miRNA) promoters in long-term night shiftworkers and day...
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