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Article

Exposure to Metal-Rich Particulate Matter Modifies the Expression of Candidate MicroRNAs in Peripheral Blood Leukocytes

8 Jan 2010

Abstract excerpt

BACKGROUND: Altered patterns of gene expression mediate the effects of particulate matter (PM) on human health, but mechanisms through which PM modifies gene expression are largely undetermined. MicroRNAs (miRNAs) are highly conserved, noncoding small RNAs that regulate the expression of broad gene networks at the posttranscriptional level. OBJECTIVES: We evaluated the effects of exposure to PM and PM metal...

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PMID: 20061215
DOI: 10.1289/ehp.0901300

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