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Article

AdHu5-apoptin induces G2/M arrest and apoptosis in p53-mutated human gastric cancer SGC-7901 cells.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2013

Li Qianqian, Zhang Hongbin, Tan Cui, Peng Weiyan, Ren Guosheng, Jia Bei, He Ying, Wang Pilong, Zhou Xiangyang, Xiang Tingxiu

Abstract excerpt

The use of anticancer therapeutic agents is limited largely by their severe toxicity to normal tissues. The development of novel agents with tumor-specific cell-killing and effective gene delivery properties is thus very desirable. We used human adenovirus serotype 5 (AdHu5) as a vehicle to deliver the apoptin gene to specifically target gastric cancer in a recombinant gene delivery approach. AdHu5-apoptin is a...

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PMID: 23812727
DOI: 10.1007/s13277-013-0936-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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