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A novel recombinant adenovirus expressing apoptin and MEL genes kills hepatocellular carcinoma cells and inhibits the growth and metastasis of ectopic tumors

2024-04-30

Abstract excerpt

<title>Abstract</title> <p>HCC is the most common fatal malignancy. Although surgical resection is the primary treatment strategy, most patients are not eligible for resection due to tumor heterogeneity, underlying liver disease, or comorbidities. Therefore, this study explores the possibility of multi-molecular targeted drug delivery in treating HCC. In this study, we constructed the recombinant adenovirus co-ex...

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Literature Corpus work
8d65369a-c85f-552a-a2e1-e5db9e807c7a
DOI
10.21203/rs.3.rs-4301482/v1
Open publication

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A novel recombinant adenovirus expressing apoptin and MEL genes kills hepatocellular carcinoma cells and inhibits the growth and metastasis of ectopic tumorsDOI 10.21203/rs.3.rs-4301482/v1
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