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Article

Rethinking mechanisms of autoimmune pathogenesis.

Journal of autoimmunity - 1 Sept 2013

Pillai Shiv

Abstract excerpt

Why exactly some individuals develop autoimmune disorders remains unclear. The broadly accepted paradigm is that genetic susceptibility results in some break in immunological tolerance, may enhance the availability of autoantigens, and may enhance inflammatory responses. Some environmental insult...

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Share to Autoimmune Diseases
Share to Epigenesis, Genetic
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Immune Tolerance

Share to Intestines

Share to Microbiota

Share to Polymorphism, Genetic

Source

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Identifiers

PMID: 23809879
DOI: 10.1016/j.jaut.2013.05.003
PMCID: PMC4820393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23809879-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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