Article
The post illumination pupil response is reduced in seasonal affective disorder.
Psychiatry research - 30 Nov 2013
Roecklein Kathryn, Wong Patricia, Ernecoff Natalie, Miller Megan, Donofry Shannon, Kamarck Marissa, Wood-Vasey W Michael, Franzen Peter
Abstract excerpt
Individuals with seasonal affective disorder (SAD) may have a decreased retinal sensitivity in the non-image forming light-input pathway. We examined the post illumination pupil response (PIPR) among individuals with SAD and healthy controls to identify possible differences in the melanopsin signaling pathway. We also investigated whether melanopsin gene (OPN4) variations would predict variability in the PIPR....
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