Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of Human Melanopsin Gene (OPN4) Polymorphisms (I394T, P10L) on Nocturnal Melatonin and Daily Rhythms in Young Adults.

Journal of pineal research - 1 Sept 2026

Vicente-Martínez Jesús, Bonmatí-Carrión María Ángeles, López-Parra Ana María, Madrid Juan Antonio, Almaida-Pagán Pedro Francisco, Rol María Angeles

Abstract excerpt

The present study investigates the impact of two missense SNPs in the human melanopsin gene OPN4 -I394T (rs1079610) and P10L (rs2675703)- on non-image-forming (NIF) physiological and behavioural outputs in healthy young adults under real-world conditions. Twenty-five healthy university students were genotyped and analysed under a C-allele dominant model for I394T and a T-allele dominant model for P10L. Over 8...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Circadian Rhythm
Share to Melatonin
Share to Polymorphism, Single Nucleotide
Share to Rod Opsins
Share to Sleep
Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42578404
DOI: 10.1111/jpi.70181
PMCID: PMC13459041

Genes

OPN4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of Human Melanopsin Gene (OPN4) Polymorphisms (I394T, P10L) on Nocturnal Melatonin and Daily Rhythms in Young Adults.PMID 42578404Read ↗

Defining the impact of melanopsin missense polymorphisms using in vivo functional rescue.Semantic proximity Read ↗

Sleep and circadian phenotype in people without cone-mediated visionSemantic proximity Read ↗

Characterizing the Modern Light Environment and its Influence on Circadian RhythmsSemantic proximity Read ↗

Association between the melanopsin gene polymorphism OPN4*Ile394Thr and sleep/wake timing in Japanese university students.Semantic proximity Read ↗

Genome-wide gene by environment study of time spent in daylight and chronotype identifies emerging genetic architecture underlying light sensitivitySemantic proximity Read ↗

Method to determine whether sleep phenotypes are driven by endogenous circadian rhythms or environmental light by combining longitudinal data and personalised mathematical models.Semantic proximity Read ↗

Method to determine whether sleep phenotypes are driven by endogenous circadian rhythms or environmental light by combining longitudinal data and personalised mathematical modelsSemantic proximity Read ↗

Hair test reveals plasticity of human chronotypeSemantic proximity Read ↗

Low-latitude environmental regularity sustains non-photic entrainment in blind adultsSemantic proximity Read ↗

CLOCK genotype modulates associations between blue light exposure and circadian activity amplitude.Semantic proximity Read ↗

Functional characterisation of naturally occurring mutations in human melanopsin.Semantic proximity Read ↗

Distinct ipRGC subpopulations mediate light's acute and circadian effects on body temperature and sleepSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.