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Article

Association between the melanopsin gene polymorphism OPN4*Ile394Thr and sleep/wake timing in Japanese university students.

Journal of physiological anthropology - 12 May 2014

Lee Sang-Il, Hida Akiko, Kitamura Shingo, Mishima Kazuo, Higuchi Shigekazu

Abstract excerpt

BACKGROUND: In our previous studies, we found that the Ile394Thr SNP in the melanopsin gene (OPN4) was functionally associated with the pupillary light reflex. This indicates the possibility that OPN4*Ile394Thr is associated with other non-image forming responses. The aim of this study was therefore to determine whether OPN4*Ile394Thr is associated with sleep/wake timing. METHODS: A total of 348 healthy Japanese...

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Source

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Identifiers

PMID: 24887407
DOI: 10.1186/1880-6805-33-9
PMCID: PMC4048048

Genes

OPN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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