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Article

Human melatonin and alerting response to blue-enriched light depend on a polymorphism in the clock gene PER3.

The Journal of clinical endocrinology and metabolism - 1 Mar 2012

Chellappa Sarah L, Viola Antoine U, Schmidt Christina, Bachmann Valérie, Gabel Virginie, Maire Micheline, Reichert Carolin F, Valomon Amandine, Götz Thomas, Landolt Hans-Peter, Cajochen Christian

Abstract excerpt

CONTEXT: Light exposure, particularly at the short-wavelength range, triggers several nonvisual responses in humans. However, the extent to which the melatonin-suppressing and alerting effect of light differs among individuals remains unknown. OBJECTIVE: Here we investigated whether blue-enriched polychromatic light impacts differentially on melatonin and subjective and objective alertness in healthy participants...

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Source

Identifiers

PMID: 22188742
DOI: 10.1210/jc.2011-2391

Genes

PER3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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