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Article

Immunogenicity analysis of Staphylococcus aureus clumping factor A genetic variants.

Clinical and vaccine immunology : CVI - 1 Aug 2013

Brady Rebecca A, Mocca Christopher P, Burns Drusilla L

Abstract excerpt

The staphylococcal adhesin clumping factor A (ClfA) has a variant amino acid sequence, generating the potential for alterations in epitope structure and immunogenicity of this vaccine candidate. We demonstrated for two recombinant ClfA(40-531) (a slightly truncated version of the fibrinogen-binding domain of ClfA containing amino acids 40 to 531) genetic variants that strain-specific epitopes are immunodominant....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23803901
DOI: 10.1128/CVI.00275-13
PMCID: PMC3754511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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