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Article

Factors affecting the immunogenicity of tetanus toxin fragment C expressed in<i>Lactococcus lactis</i>

1 Jun 1996

Abstract excerpt

The relative immunogenicity of tetanus toxin fragment C (TTFC) has been determined in three different strains of inbred mice when expressed in Lactococcus lactis as a membrane-anchored protein (strain UCP1054), as an intracellular protein (strain UCP1050), or as a secreted protein which is partly retained within the cell wall (strain UCP1052). Protection against toxin challenge (20 x LD50) could be obtained...

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PMID: 8809553
DOI: 10.1111/j.1574-695x.1996.tb00284.x

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