Article
MiR-133a modulates osteogenic differentiation of vascular smooth muscle cells.
Endocrinology - 1 Sept 2013
Liao Xiao-Bo, Zhang Zhi-Yuan, Yuan Ke, Liu Yuan, Feng Xiang, Cui Rong-Rong, Hu Ye-Rong, Yuan Zhao-Shun, Gu Lu, Li Shi-Jun, Mao Ding-An, Lu Qiong, Zhou Xin-Ming, de Jesus Perez Vinicio A, Yuan Ling-Qing
Abstract excerpt
Arterial calcification is a key pathologic component of vascular diseases such as atherosclerosis, coronary artery disease, and peripheral vascular disease. A hallmark of this pathological process is the phenotypic transition of vascular smooth muscle cells (VSMCs) to osteoblast-like cells. Several studies have demonstrated that microRNAs (miRNAs) regulate osteoblast differentiation, but it is unclear whether...
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