Article
Outcomes of atypical spitz tumors with chromosomal copy number aberrations and conventional melanomas in children.
The American journal of surgical pathology - 1 Sept 2013
Gerami Pedram, Cooper Chelsea, Bajaj Shirin, Wagner Annette, Fullen Douglas, Busam Klaus, Scolyer Richard A, Xu Xiaowei, Elder David E, Abraham Ronnie M, Prieto Victor G, Guitart Joan, Liu Ping, Pestova Ekaterina, Barnhill Raymond L
Abstract excerpt
Death due to melanoma in childhood (up to 20 y of age) is a rare event, with an average of 18 cases reported annually in the United States. In this study we evaluated 2 subgroups of high-risk melanocytic neoplasms in childhood, specifically atypical Spitz tumors (ASTs) with chromosomal copy number changes and conventional melanomas. We analyzed the clinical, histologic, and molecular features of all cases and...
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