Article
The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity.
Psychoneuroendocrinology - 1 Oct 2013
Logue Mark W, Solovieff Nadia, Leussis Melanie P, Wolf Erika J, Melista Efthymia, Baldwin Clinton, Koenen Karestan C, Petryshen Tracey L, Miller Mark W
Abstract excerpt
BACKGROUND: The ankyrin 3 gene (ANK3) produces the ankyrin G protein that plays an integral role in regulating neuronal activity. Previous studies have linked ANK3 to bipolar disorder and schizophrenia. A recent mouse study suggests that ANK3 may regulate behavioral disinhibition and stress reactivity. This led us to hypothesize that ANK3 might also be associated with stress-related psychopathology such as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.