Article
Polymorphisms of base-excision repair genes and the hepatocarcinogenesis.
Gene - 30 Oct 2018
Mattar Manar-Aleslam M, Zekri Abdel-Rahman N, Hussein Nehal, Morsy Heba, Esmat Gamal, Amin Magdy A
Abstract excerpt
AIM: To determine the possible association between polymorphisms of DNA repair genes, including XRCC1 Arg194Tryp, Arg280His, and Arg399Glu, APE1 Asp148Glu, and NEIL2 Arg257Leu, and the risk of developing hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS: A total of 264 subjects were recruited in this retrospective case-control study and were categorized into four groups: 88 control subjects...
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