Article
Tumour morphology predicts PALB2 germline mutation status.
British journal of cancer - 9 Jul 2013
Teo Z L, Provenzano E, Dite G S, Park D J, Apicella C, Sawyer S D, James P A, Mitchell G, Trainer A H, Lindeman G J, Shackleton K, Cicciarelli L, Buys S S, Andrulis I L, Mulligan A M, Glendon G, John E M, Terry M B, Daly M, Odefrey F A, Nguyen-Dumont T, Giles G G, Dowty J G, Winship I, Goldgar D E, Hopper J L, Southey M C
Abstract excerpt
BACKGROUND: Population-based studies of breast cancer have estimated that at least some PALB2 mutations are associated with high breast cancer risk. For women carrying PALB2 mutations, knowing their carrier status could be useful in directing them towards effective cancer risk management and therapeutic strategies. We sought to determine whether morphological features of breast tumours can predict PALB2 germline...
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