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Article

What is the phenotype of patients with gastrointestinal intolerance to metformin?

Diabetes & metabolism - 1 Sept 2013

Hermans M P, Ahn S A, Rousseau M F

Abstract excerpt

BACKGROUND: A substantial minority of type 2 diabetes mellitus (T2DM) patients treated with metformin develop severe gastrointestinal (GI) symptoms leading to drug discontinuation, depriving them of the potentially cardioprotective pleiotropic effects of this first-line oral agent. At present, it is unclear whether treating diabetes without being able to ever use metformin alters cardiovascular outcomes. PATIENTS...

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PMID: 23786968
DOI: 10.1016/j.diabet.2013.05.005

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ABO
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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