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Article

Role of IL28B gene polymorphism and cell-mediated immunity in spontaneous resolution of acute hepatitis C.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Sept 2013

Spada Enea, Amoroso Pietro, Taliani Gloria, Zuccaro Ornella, Chiriacò Piergiorgio, Maio Patrizia, Maio Giuseppe, Esposito Maria Luisa, Mariano Corrado, Rinaldi Roberto, Bellissima Pietro, Tosti Maria Elena, Del Porto Paola, Francavilla Ruggiero, Mellace Vincenzo, Garbuglia Anna Rosa, Folgori Antonella, Mele Alfonso

Abstract excerpt

BACKGROUND: A single-nucleotide polymorphism (SNP; rs12979860) near the IL28B gene has been associated with spontaneous and treatment-induced hepatitis C virus clearance. We investigated predictors of spontaneous disease resolution in a cohort of patients with acute hepatitis C (AHC), analyzing epidemiological, clinical and virological parameters together with IL28B.rs12979860 genotypes and cell-mediated immunity...

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Identifiers

PMID: 23784926
DOI: 10.1093/cid/cit402
PMCID: PMC3749747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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