Article
High frequency of the X-chromosome inactivation in young female patients with high-grade glioma.
Diagnostic pathology - 19 Jun 2013
Li Gang, Zhang Zhiguo, Jin Tianbo, Liang Hongjuan, Tu Yanyang, Gong Li, Chen Zhongping, Gao Guodong
Abstract excerpt
BACKGROUND: Gliomas are common tumors and high-grade ones account for 62% of primary malignant brain tumors. Though current evidence have suggested that inherited risks play a role in glioma susceptibility, it was conveyed that glioma was such a complex disease, and the direct genetic contribution to glioma risk factors and its relation to other factors should be discussed more deeply. X-chromosome inactivation...
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