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Article

Bioelectric characterization of epithelia from neonatal CFTR knockout ferrets.

American journal of respiratory cell and molecular biology - 1 Nov 2013

Fisher John T, Tyler Scott R, Zhang Yulong, Lee Ben J, Liu Xiaoming, Sun Xingshen, Sui Hongshu, Liang Bo, Luo Meihui, Xie Weiliang, Yi Yaling, Zhou Weihong, Song Yi, Keiser Nicholas, Wang Kai, de Jonge Hugo R, Engelhardt John F

Abstract excerpt

Cystic fibrosis (CF) is a life-shortening, recessive, multiorgan genetic disorder caused by the loss of CF transmembrane conductance regulator (CFTR) chloride channel function found in many types of epithelia. Animal models that recapitulate the human disease phenotype are critical to understanding pathophysiology in CF and developing therapies. CFTR knockout ferrets manifest many of the phenotypes observed in...

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Identifiers

PMID: 23782101
DOI: 10.1165/rcmb.2012-0433OC
PMCID: PMC3931095

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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