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PEG1/MEST and IGF2 DNA methylation in CIN and in cervical cancer

17 Jun 2013

Abstract excerpt

INTRODUCTION: Although most invasive cervical cancer (ICC) harbor <20 human papillomavirus (HPV) genotypes, use of HPV screening to predict ICC from HPV has low specificity, resulting in multiple and costly follow-up visits and overtreatment. We examined DNA methylation at regulatory regions of imprinted genes in relation to ICC and its precursor lesions to determine if methylation profiles are associated with...

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Share to Cervical Cancer and HPV Research
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PMID: 23775149
DOI: 10.1007/s12094-013-1067-4

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