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Article

Polymorphisms in TREX1 and susceptibility to HIV-1 infection.

International journal of immunogenetics - 1 Dec 2013

Pontillo A, Girardelli M, Catamo E, Duarte A J, Crovella S

Abstract excerpt

TREX-1 is a restriction factor against HIV-1. The coding sequence of TREX1 gene was analysed in HIV+ subjects searching for genetic variations possibly associated with the susceptibility to HIV infection. The single nucleotide polymorphism rs3135945 was significantly associated with HIV infection, emphasizing the involvement of TREX-1 in the anti-HIV response.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23773365
DOI: 10.1111/iji.12071

Genes

TREX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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