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Article

Identification of Polymorphisms in EAAT1 Glutamate Transporter Gene SLC1A3 Associated with Reduced Migraine Risk.

Genes - 18 Jun 2024

Albury Cassie L, Sutherland Heidi G, Lam Alexis W Y, Tran Ngan K, Lea Rod A, Haupt Larisa M, Griffiths Lyn R

Abstract excerpt

Dysfunction in ion channels or processes involved in maintaining ionic homeostasis is thought to lower the threshold for cortical spreading depression (CSD), and plays a role in susceptibility to associated neurological disorders, including pathogenesis of a migraine. Rare pathogenic variants in specific ion channels have been implicated in monogenic migraine subtypes. In this study, we further examined the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38927733
DOI: 10.3390/genes15060797
PMCID: PMC11202508

Genes

SLC1A3
CHRNA4
SLC4A4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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