Article
Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility.
BMC medical genetics - 25 Jun 2010
Formicola Daniela, Aloia Andrea, Sampaolo Simone, Farina Olimpia, Diodato Daria, Griffiths Lyn R, Gianfrancesco Fernando, Di Iorio Giuseppe, Esposito Teresa
Abstract excerpt
BACKGROUND: Glutamate is the principal excitatory neurotransmitter in the central nervous system which acts by the activation of either ionotropic (AMPA, NMDA and kainate receptors) or G-protein coupled metabotropic receptors. Glutamate is widely accepted to play a major role in the path physiolo...
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