Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia.

doi:10.1128/JB.00183-12

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Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia.

Journal of bacteriology - 1 Jun 2012

Trost Eva, Blom Jochen, Soares Siomar de Castro, Huang I-Hsiu, Al-Dilaimi Arwa, Schröder Jasmin, Jaenicke Sebastian, Dorella Fernanda A, Rocha Flavia S, Miyoshi Anderson, Azevedo Vasco, Schneider Maria P, Silva Artur, Camello Thereza C, Sabbadini Priscila S, Santos Cíntia S, Santos Louisy S, Hirata Raphael, Mattos-Guaraldi Ana L, Efstratiou Androulla, Schmitt Michael P, Ton-That Hung, Tauch Andreas

Abstract excerpt

Corynebacterium diphtheriae is one of the most prominent human pathogens and the causative agent of the communicable disease diphtheria. The genomes of 12 strains isolated from patients with classical diphtheria, endocarditis, and pneumonia were completely sequenced and annotated. Including the genome of C. diphtheriae NCTC 13129, we herewith present a comprehensive comparative analysis of 13 strains and the...

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PMID: 22505676
DOI: 10.1128/JB.00183-12
PMCID: PMC3370855

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