Article
Infection by a multidrug-resistant Corynebacterium diphtheriae strain: prediction of virulence factors, CRISPR-Cas system analysis, and structural implications of mutations conferring rifampin resistance.
Functional & integrative genomics - 28 Aug 2024
Araújo Max Roberto Batista, Prates Fernanda Diniz, Ramos Juliana Nunes, Sousa Eduarda Guimarães, Bokermann Sérgio, Sacchi Cláudio Tavares, de Mattos-Guaraldi Ana Luiza, Campos Karoline Rodrigues, Sousa Mireille Ângela Bernardes, Vieira Verônica Viana, Santos Marlon Benedito Nascimento, Camargo Carlos Henrique, de Oliveira Sant'Anna Lincoln, Dos Santos Louisy Sanches, Azevedo Vasco
Abstract excerpt
Cases of diphtheria, even in immunized individuals, are still reported in several parts of the world, including in Brazil. New outbreaks occur in Europe and other continents. In this context, studies on Corynebacterium diphtheriae infections are highly relevant, both for a better understanding of the pathogenesis of the disease and for controlling the circulation of clones and antimicrobial resistance genes. Here...
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