Article
Candida albicans forms a specialized "sexual" as well as "pathogenic" biofilm.
Eukaryotic cell - 1 Aug 2013
Park Yang-Nim, Daniels Karla J, Pujol Claude, Srikantha Thyagarajan, Soll David R
Abstract excerpt
Candida albicans forms two types of biofilm in RPMI 1640 medium, depending upon the configuration of the mating type locus. In the prevalent a/α configuration, cells form a biofilm that is impermeable, impenetrable by leukocytes, and fluconazole resistant. It is regulated by the Ras1/cyclic AMP (cAMP) pathway. In the a/a or α/α configuration, white cells form a biofilm that is architecturally similar to an a/α...
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