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Article

Huntington's disease: underlying molecular mechanisms and emerging concepts.

Trends in biochemical sciences - 1 Aug 2013

Labbadia John, Morimoto Richard I

Abstract excerpt

Huntington's disease (HD) is a progressive neurodegenerative disorder for which no disease modifying treatments exist. Many molecular changes and cellular consequences that underlie HD are observed in other neurological disorders, suggesting that common pathological mechanisms and pathways may exist. Recent findings have enhanced our understanding of the way cells regulate and respond to expanded polyglutamine...

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Identifiers

PMID: 23768628
DOI: 10.1016/j.tibs.2013.05.003
PMCID: PMC3955166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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