Article
Allele-specific expression of the serotonin transporter and its transcription factors following lamotrigine treatment in vitro.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2013
D'Souza Ursula M, Powell-Smith Georgia, Haddley Kate, Powell Timothy R, Bubb Vivien J, Price Tom, McGuffin Peter, Quinn John P, Farmer Anne E
Abstract excerpt
Lamotrigine, a mood stabilizer used clinically in the treatment of bipolar disorder, is thought to exert actions on the serotonin system. However lamotrigine's exact mechanism of action remains unclear. The current study investigated whether lamotrigine might exert its effects through altering th...
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