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Article

Modulation of human serotonin transporter expression by 5-HTTLPR in colon cells.

International journal of molecular sciences - 1 Jan 2011

Prasansuklab Anchalee, Poovorawan Yong, Tencomnao Tewin

Abstract excerpt

Serotonin (5-HT) is a monoamine neurotransmitter and plays important roles in several of the human body's systems. Known as a primary target for psychoactive drug development, the 5-HT transporter (5-HTT, SERT) plays a critical role in the regulation of serotonergic function by reuptaking 5-HT. The allelic variation of 5-HTT expression is caused by functional gene promoter polymorphism with two principal variant...

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Identifiers

PMID: 22072907
DOI: 10.3390/ijms12106619
PMCID: PMC3210998

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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