Article
Common genetic variants in the microRNA biogenesis pathway are associated with malignant peripheral nerve sheath tumor risk in a Chinese population.
Cancer epidemiology - 1 Dec 2013
Weng Yuxiong, Chen Yanhua, Chen Jianghai, Liu Yutian, Bao Tengfei
Abstract excerpt
PURPOSE: The role of microRNAs (miRNAs) in tumorigenesis has been well established. Genetic variants in the miRNA biogenesis pathway genes may modify cancer development and survival by affecting the miRNA biogenesis. Our aim is to investigate the association of polymorphisms in the miRNA biogenesis pathway genes and malignant peripheral nerve sheath tumor (MPNST) risk among neurofibromatosis type 1 (NF1)...
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