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MicroRNA Biogenesis Pathway Gene Variants Are Associated with Prostate Cancer Susceptibility.

International journal of molecular sciences - 20 Jun 2026

Gilyazova Irina, Timasheva Yanina, Ivanova Elizaveta, Gimalova Galiya, Izmailov Adel, Abdeeva Gulshat, Dzaubermezov Murat, Balkhiyarova Zhanna, Prokopenko Inga, Pavlov Valentin, Khusnutdinova Elza

Abstract excerpt

Prostate cancer (PrC) is one of the most common malignancies among men worldwide. However, the contribution of genetic variation in microRNA (miRNA) biogenesis pathway genes to PrC susceptibility remains poorly characterized in many ethnically diverse populations. We conducted a case-control study involving 532 PrC patients and 550 controls from the Volga-Ural region of Eurasia to evaluate the association of...

Topics

Humans
MicroRNAs
Prostatic Neoplasms
Male
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide
Genetic Risk Score
Case-Control Studies
Middle Aged
Argonaute Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Eukaryotic Initiation Factors

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Open in PubMed Open full text

Identifiers

PMID: 42353292
DOI: 10.3390/ijms27125578
PMCID: PMC13299046

Genes

AGO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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