Article
Reverse mutation of the virulence-associated S2 gene does not cause an attenuated equine infectious anemia virus strain to revert to pathogenicity.
Virology - 1 Sept 2013
Gao Xu, Jiang Cheng-Gang, Wang Xue-Feng, Lin Yue-Zhi, Ma Jian, Han Xiu-E, Zhao Li-Ping, Shen Rong-Xian, Xiang Wen-Hua, Zhou Jian-Hua
Abstract excerpt
The contribution of S2 accessory gene of equine infectious anemia virus (EIAV) to the virulence of pathogenic strains was investigated in the present study by reverse mutation of all four consensus S2 mutation sites in an attenuated EIAV proviral strain, FDDV3-8, to the corresponding sequences of...
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